La importancia de la contribución paterna en el desarrollo  embrionario: los ARN espermáticos

David García Valcarce; Florentino Garrido Gonzalez; Elsi Suárez Álvarez; Ángel J. Luengos Martínez; Vanesa Robles Rodríguez

doi:10.18002/ambioc.v0i10.4940

Autores/as

David García Valcarce
Florentino Garrido Gonzalez
Elsi Suárez Álvarez
Ángel J. Luengos Martínez
Vanesa Robles Rodríguez

DOI:

https://doi.org/10.18002/ambioc.v0i10.4940

Palabras clave:

Genética, Medicina. Salud, ARNm, Humano, ARTs, Biotecnología, Sémen,

Resumen

Estudios clínicos han descrito una mayor incidencia de ciertas enfermedades en los nacidos a partir de tecnologías de reproducción asistida. Durante los últimos años se ha demostrado que algunos de los ARN mensajeros pueden tener un importante papel como marcadores de interés clínico. Además, cada vez se confirma en mayor medida que estas moléculas tienen un importante papel en las primeras etapas del desarrollo embrionario. En este trabajo se describen las diferentes poblaciones de ARN espermáticas y sus posibles usos como herramientas diagnósticas en clínica

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Citas

Abraham, K.A. y Bhargava, P.M. (1963). The uptake of radioactive amino acids by spermatozoa.The intracellular site of incorporation into proteins. Biochemical Journal. 86: 308-313.

Amanai, M., Brahmajosyula, M. y Perry, A.C. (2006). A restricted role for spermborne microRNAs in mammalian fertilization. Biology of Reproduction. 75: 877-884.

Betlach, C.J. y Erickson, R.P. (1973). A unique RNA species from maturing mouse spermatozoa. Nature. 242: 114-115.

Boerke, A., Dieleman, S.J. y Gadella, B.M. (2007). A possible role for sperm RNA in early embryo development. Theriogenology. 68 Suppl 1: S147-55.

Carrell, D.T. y Hammoud, S.S. (2010). The human sperm epigenome and its potential role in embryonic development. Molecular Human Reproduction. 16: 37-47.

Dadoune, J.P., Pawlak, A., Alfonsi, M.F. y Siffroi, J.P. (2005). Identification of transcripts by macroarrays, RT-PCR and in situ hybridization in human ejaculate spermatozoa. Molecular Human Reproduction. 11: 133-140.

De Ambrogi, M., Spinaci, M., Galeati, G. y Tamanini, C. (2007). Leptin receptor in boar spermatozoa. International Journal of Andrology. 30: 458-461.

Depa-Martynow, M., Kempisty, B., Lianeri, M., Jagodzinski, P.P. y Jedrzejczak, P. (2007). Association between fertilin beta, protamines 1 and 2 and spermatidspecific linker histone H1-like protein mRNA levels, fertilization ability of human spermatozoa, and quality of preimplantation embryos. Folia Histochemica et Cytobiologica. 45 Suppl 1: S79-85.

García-Herrero, S., Garrido, N., Martinez-Conejero, J.A., Remohi, J., Pellicer, A. y Meseguer, M. (2011). Differential transcriptomic profile in spermatozoa achieving pregnancy or not via ICSI. Reproductive Biomedicine Online. 22: 25-36.

García-Herrero, S., Meseguer, M., Martinez-Conejero, J.A., Remohi, J., Pellicer, A. y Garrido, N. (2010). The transcriptome of spermatozoa used in homologous intrauterine insemination varies considerably between samples that achieve pregnancy and those that do not. Fertility and Sterility. 94: 1360- 1373.

Gil Villa, A.M., Cardona-Maya, W.D. y Cadavid Jaramillo, A.P. (2007). Early embryo death: Does the male factor play a role? Archivos Españoles de Urología. 60: 1.057-68.

Gilbert, I., Bissonnette, N., Boissonneault, G., Vallee, M. y Robert, C. (2007). A molecular analysis of the population of mRNA in bovine spermatozoa. Reproduction. 133: 1073-1086.

Gur, Y. y Breitbart, H. (2006). Mammalian sperm translate nuclear-encoded proteins by mitochondrial-type ribosomes. Genes & Development. 20:411- 416.

Hayashi, S., Yang J., Christenson, L., Yanagimachi, R. y Hecht, N.B. (2003). Mouse preimplantation embryos developed from oocytes injected with round spermatids or spermatozoa have similar but distinct patterns of early messenger RNA expression. Biology of Reproduction. 69:1170-1176.

Lalancette, C., Miller, D., Li, Y. y Krawetz, S.A. (2008). Paternal contributions: New functional insights for spermatozoal RNA. Journal of Cellular Biochemistry. 104:1570-1579.

Maher, E.R., Afnan, M. y Barratt, C.L. (2003ª). Epigenetic risks related to assisted reproductive technologies: Epigenetics, imprinting, ART and icebergs? Human Reproduction. 18: 2508-2511.

Maher, E.R., Brueton, L.A., Bowdin, S.C., Luharia, A., Cooper, W., Cole, T.R., et al. (2003b). Beckwith-wiedemann syndrome and assisted reproduction technology (ART). Journal of Medical Genetics. 40: 62-64.

Miller, D., Ostermeier, G.C. y Krawetz, S.A. (2005). The controversy, potential and roles of spermatozoal RNA. Trends in Molecular Medicine. 11:156-163.

Ostermeier, G.C., Miller, D., Huntriss, J.D., Diamond, M.P. y Krawetz, S.A. (2004). Reproductive biology: Delivering spermatozoan RNA to the oocyte. Nature. 429:154.

Platts, A.E., Dix, D.J., Chemes, H.E., Thompson, K.E., Goodrich, R., Rockett, J.C., et al. (2007). Success and failure in human spermatogenesis as revealed by teratozoospermic RNAs. Human Molecular Genetics. 16:763-773.

Rassoulzadegan, M., Grandjean, V., Gounon, P., Vincent, S., Gillot, I. y Cuzin, F. (2006). RNA-mediated non-mendelian inheritance of an epigenetic change in the mouse. Nature. 441 469-474.

Stitzel, M.L. y Seydoux, G. (2007). Regulation of the oocyte-to-zygote transition. Science. 316:407-408.

Swann, K., Larman, M.G., Saunders, C.M. y Lai, F.A. (2004). The cytosolic sperm 2+ factor that triggers Ca oscillations and egg activation in mammals is a novel phospholipase C: PLCzeta. Reproduction. 127:431-439.

Ward, W.S., Kishikawa, H., Akutsu, H., Yanagimachi, H. y Yanagimachi, R. (2000). Further evidence that sperm nuclear proteins are necessary for embryogenesis. Zygote. 8:51-56.

Wu, S.F., Zhang, H. y Cairns B.R. (2011). Genes for embryo development are packaged in blocks of multivalent chromatin in zebrafish sperm. Genome Research. 21: 578-589.

Zini, A., Boman, J.M., Belzile, E. y Ciampi, A. (2008). Sperm DNA damage is associated with an increased risk of pregnancy loss after IVF and ICSI: Systematic review and meta-analysis. Human Reproduction. 23:2663- 2668.